May 2024

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Paris — Climate change played a key role in last year’s record-low levels of Antarctic sea ice, a study published on Monday found, marking an abrupt shift from the growth seen in previous decades.

Scientists from the British Antarctic Survey (BAS) found that human-caused global warming resulted in a once-in-2,000-year low in ocean surface around the continent blanketed by ice.

Compared to an average winter over the last several decades, the maximum extent of Antarctic sea covered by ice shrank by two million square kilometers — an area four times the size of France, the BAS said.

“This is why we were so interested in studying what climate models can tell us about how often large, rapid losses like this are likely to happen,” the study’s lead author Rachel Diamond told AFP.

Scientists, having analyzed 18 distinct climate models, found that climate change quadrupled the likelihood of such large and rapid melting events.

Understanding the cause of sea ice melt is complex as there are many variables — from ocean water to air temperature to winds — that can effect it, scientists say.

But determining the role of climate change is critical since ice formation has global impacts from ocean currents to sea-level rise.

Sea ice, which forms from freezing salt water already in the ocean, has no discernible impact on sea levels.

But when highly reflective snow and ice give way to dark blue ocean, the same amount of the Sun’s energy that was bounced back into space is absorbed by water instead, accelerating the pace of global warming.

Recovery unlikely

Unlike the Arctic, where sea ice has been declining since satellite records began in the 1970s, the melt trend in Antarctica is a more recent phenomenon.

Antarctic sea ice increased “slightly and steadily” from 1978 until 2015, according to the BAS.

But 2017 brought a sharp decline, followed by several years of low ice levels.

In the study published in the journal Geophysical Research Letters, BAS researchers also ran projections to see whether the ice would return.

“It doesn’t completely recover to original levels even after 20 years,” Diamond told AFP. That means “the average Antarctic sea ice may still stay relatively low for decades to come”, he added.

“The impacts… would be profound, including on local and global weather and on unique Southern Ocean ecosystems — including whales and penguins,” co-author Louise Sime said.

Previous studies by the BAS have shown that the abnormal melt has led to the deaths of thousands of emperor penguin chicks.

Reared on the ice sheets, they perished when they were plunged into the ocean before they had developed their waterproof feathers.
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SYDNEY — Researchers in Australia and the United States say that a new artificial intelligence tool has allowed them to classify brain tumors more quickly and accurately.  

The current method for identifying different kinds of brain tumors, while accurate, can take several weeks to produce results.  The method, called DNA methylation-based profiling, is not available at many hospitals around the world.

To address these challenges, a research team from the Australian National University, in collaboration with the National Cancer Institute in the United States, has developed a way to predict DNA methylation, which acts like a switch to control gene activity.  

This allows them to classify brain tumors into 10 major categories using a deep learning model.

This is a branch of artificial intelligence that teaches computers to process data in a way that is inspired by a human brain.

The joint U.S.-Australian system is called DEPLOY and uses microscopic pictures of a patient’s tissue called histopathology images.

The researchers see the DEPLOY technology as complementary to an initial diagnosis by a pathologist or physician.

Danh-Tai Hoang, a research fellow at the Australian National University, told VOA that AI will enhance current diagnostic methods that can often be slow.

“The technique is very time consuming,” Hoang said. “It is often around two to three weeks to obtain a result from the test, whereas patients with high-grade brain tumors often require treatment as soon as possible because time is the goal for brain tumor(s), so they need to get treatment as soon as possible.”

The research team said its AI model was validated on large datasets of approximately 4,000 patients from across the United States and Europe and an accuracy rate of 95 percent.

Their study has been published in the journal Nature Medicine.
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London — The final report of the U.K.’s infected blood inquiry will be published Monday, nearly six years after it began looking into how tens of thousands of people contracted HIV or hepatitis from transfusions of tainted blood and blood products in the 1970s and 1980s.

The scandal is widely seen as the deadliest to afflict Britain’s state-run National Health Service since its inception in 1948, with around 3,000 people believed to have died as a result of being infected with HIV and hepatitis, an inflammation of the liver.

The report is expected to criticize pharmaceutical firms and medical practitioners, civil servants and politicians, although many have already died given the passage of time. It’s also set to pave the way to a huge compensation bill that the British government will be under pressure to rapidly pay out.

Had it not been for the tireless campaigners, many of whom saw loved ones die decades too soon, the scale of the scandal may have remained hidden forever.

“This whole scandal has blanketed my entire life,” said Jason Evans, who was four when his father died at the age of 31 in 1993 after contracting HIV and hepatitis from an infected blood plasma product.

“My dad knew he was dying and he took many home videos, which I’ve got and replayed over and over again growing up because that’s really all I had,” he added.

Evans was instrumental in the decision by then-Prime Minister Theresa May to establish the inquiry in 2017. He said he just “couldn’t let it go.” His hope is that on Monday, he and countless others, can.

Here is a look at what the scandal was about and what the report’s impact may be.

What is the infected blood scandal?

In the 1970s and 1980s, thousands of people who needed blood transfusions, for example after childbirth or surgery, became exposed to blood tainted with hepatitis, including an as yet unknown kind that was later termed Hepatitis C, and HIV.

Those with haemophilia, a condition affecting the blood’s ability to clot, became exposed to what was sold as a revolutionary new treatment derived from blood plasma.

In the U.K., the NHS, which treats the majority of people, started using the new treatment in the early 1970s. It was called Factor VIII. It was more convenient when compared with an alternative treatment and was dubbed a wonder drug.

Demand soon outstripped domestic sources of supply, so health officials began importing Factor VIII from the U.S., where a high proportion of plasma donations came from prisoners and drug users who were paid to donate blood. That dramatically raised the risk of the plasma being contaminated.

Factor VIII was made by mixing plasma from thousands of donations. In this pooling, one infected donor would compromise the whole batch.

The inquiry heard estimates that more than 30,000 people were infected from compromised blood or blood products via transfusions or Factor VIII.

Missed chances

By the mid 1970s, there was evidence haemophiliacs being treated with Factor VIII were more prone to hepatitis. The World Health Organization, which had warned in 1953 of the hepatitis risks associated with the mass pooling of plasma products, urged countries not to import plasma.

AIDS, the biggest public health crisis since World War II, turned up in the early 1980s. Originally thought to be isolated to the gay community, it soon started appearing among haemophiliacs and those who had received blood transfusions.

Though the cause of AIDS — HIV — was not identified until 1983, warnings had been relayed to the U.K. government the year before that the causative agent could be transmitted by blood products. The government argued there was no conclusive proof. Patients were not informed of the risk and persisted with a treatment that put them in mortal danger.

Mistakes

The inquiry is expected to conclude that lessons from as early as the 1940s had been ignored.

Campaigners argue that since the 1940s it had been clear that heat killed hepatitis in another plasma product, albumin. They say authorities could have made Factor VIII safe before it was sold.

Evidence given to the inquiry suggested that authorities’ main objection was financial. Non-heated Factor VIII was prescribed by the NHS until late 1985.

Campaigners hope the inquiry’s core finding is that Factor VIII concentrates should never have been licensed for use unless heated.

Why now?

In the late 1980s, victims and their families called for compensation on the grounds of medical negligence. Though the government set up a charity to make one-off support payments to those infected with HIV in the early 1990s, it did not admit liability or responsibility and victims were pressured to sign a waiver undertaking not to sue the Department of Health to get the money.

Crucially, the waiver also prevented victims from suing for hepatitis, even though at that stage they only knew about their HIV infection. Years after signing, victims were told they had also been infected with hepatitis, mainly Hepatitis C.

There was no further group litigation until Evans, whose mother “crumbled” after his father’s death and who was called “AIDS boy” at school, brought a case claiming misfeasance in public office against the Department of Health.

Combined with political and media pressure, May announced the independent inquiry. It was, she said, “an appalling tragedy which should simply never have happened.”

Compensation

The government has accepted the case for compensation, with most estimates putting the final bill in the region of $12.7 billion. In October 2022, authorities made interim payments of 100,000 pounds to each survivor and bereaved partners.

The government is expected to announce different payments for different infections and address how and when bereaved families can apply for interim payments on behalf of the estates of people who have died.
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